Atopic Dermatitis
Conditions
Interventions
Case series:Compound Glycyrrhizin Capsules, 75mg tid
Sponsors
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The diagnosis of AD was confirmed according to the Williams diagnostic criteria. The severity of AD was assessed based on the Rajka and Langeland criteria. At least 10% body surface was affected by the disease (palm method). Patients with the eczema area and severity index (EASI) between 7-14 were considered moderate to severe AD.
Exclusion criteria
Exclusion criteria: Patients, who were pregnant, had autoimmune diseases, chronic systemic disease, and/or other skin diseases, or had a history of tumor or familial tumor diseases were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cell counts of CD4+CD25+FoxP3+T regulatory cells (Tregs), CD4+CD25+FoxP3-T effector cells (Teffs), and CD4+IL-10+Tregs were analyzed by flow cytometry.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum levels of IL-4, IL-10, IL-12, IL-13, IFN-?, and TGF-ß were measured by ELISA.; | — |
Countries
China
Contacts
Public ContactLinfeng Li
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed