Right-sided colon cancer
Conditions
Interventions
B(control group):Laparoscopic surgery
Sponsors
the First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 80 years; (2) The tumor is located in the right-sided colon: ileus, ascending colon, liver curvature of colon , right 1/3 of transverse colon; (3) Pathologic biopsy confirmed the right-sided colon adenocarcinoma; (4) Preoperative clinical stage: locally advanced right-sided colon adenocarcinoma(cT2-4,N0-2,M0AJCC-8); (5) R0 results are expected from right hemicolectomy and regional lymph node dissection; (6) Preoperative ECOG physical state score: 0/1; (7) Preoperative ASA score: I-III; (8) Patient or family members understand the research program and are willing to participate in this study and sign written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe mental illness; 2. Emergency surgery for acute intestinal obstruction, bleeding and perforation in the right-sided colon adenocarcinoma; 3. Multiple primary colorectal malignant tumors; 4. Family adenomatosis (FAP), Lynch syndrome, inflammatory bowel disease; 5. Patients with right-sided colon adenocarcinoma who have undergone new adjuvant therapy before surgery; 6. History of abdominal surgery; 7. Pregnant or lactating women; 8. There were other malignant diseases within 5 years; 9. There were simultaneous surgical treatment for other diseases; 10. There were continuous systemic corticosteroid therapy within 1 month; 11. There were unstable angina or myocardial infarction within 6 months; 12. There were cerebral infarction or cerebral hemorrhage within 6 months; 13. Pulmonary function test FEV1< 50%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year disease-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-year overall survival;5-year disease-free and overall survival;3/5-year locoregional recurrence rate;postoperative complication rate;operative duration;estimated blood loss;postoperative complications;conversion to open surgery;Postoperative recovery time;length of postoperative hospital stay;postoperative 30-day mortality rate;Postoperative quality of life; | — |
Countries
China
Contacts
Public ContactTaiyuan Li
the First Affiliated Hospital of Nanchang University
Outcome results
None listed