allergic rhinitis
Conditions
Interventions
the control group:subcutaneous immunotherapy
the test group:intralymphatic immunotherapy
Sponsors
the First People's Hospital of Foshan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 5-65 years; 2. According to the diagnostic standards of Diagnosis and Treatment Guideline of Allergic Rhinitis (2015,Tianjin): two symptoms or above of sneezing, watery rhinorrhea, nasal itch and nasal obstruction, which last or accumulate to 1 hour a day, and may be accompanied with ocular symptoms such as itch, lacrimation and redness; 3. Signs: pale nasal mucosa, edema and watery secretion; 4. Allergen detection: positive reaction to house dust mite and Dermatophagoides farine in skin prick test (level 2 or above) and or serum specific IgE of house dust mite and Dermatophagoides farine greater than or equal to 0.70kU/L. Patients who are satisfied with cervical lymphatic injection or skin injection and willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. severe and uncontrolled asthma or irreversible airway obstructive diseases; 2. use of ß-blockers or ACEI; 3. serious cardiovascular diseases; 4. serious immunologic diseases; 5. severe psychiatric disorders or patients who can not understand risks and limitations of treatment; 6. malignancies; 7. pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue score;medication score;rhinoconjunctivitis quality of life questionnaire;nasal resistance and acoustic rhinometry;adverse reactions; | — |
Countries
China
Contacts
Public ContactJun Tang
the First People's Hospital of Foshan
Outcome results
None listed