periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Aggressive Periodontitis: according to the AgP diagnostic criteria established by the international symposium on classification of periodontal diseases in 1999 (1) Aged 18 to 35 years old; (2) Rapid alveolar bone destruction and attachment loss: the probing depth of at least 6 teeth (at least 3 of them are non-first molars and incisors) in the whole mouth is greater than 5mm, and the adjacent attachment loss is greater than 3mm. All were confirmed to have alveolar bone resorption on the adjacent surface by periapical films; (3) Did not receive periodontal treatment within 6 months before treatment, and did not take antibacterial drugs for nearly 3 months; (4) There are at least 20 remaining teeth in the whole mouth except the third molars, and at least one molar in each section; Chronic periodontitis: according to the CP diagnostic criteria established by the international symposium on classification of periodontal diseases in 1999; (1) The patient's onset age was between 35 and 60 years old; (2) The patient was systematically healthy, had gingival bleeding, swelling, pain, halitosis, teeth mobility and occlusion discomfort; (3) At least one molar exists in each section.At least two sites in each quadrant with probing depth greater than 5mm and attachment loss greater than 3mm; (4) At least 50% of all teeth in the whole mouth have the following conditions :(a) there exists sites with probing depth greater than 5mm;(b) alveolar bone absorption is greater than or equal to 30%;(c) bleeding on probing or periodontal abscess; (5) Did not receive periodontal treatment within 6 months before treatment, and did not take antibacterial drugs for nearly 3 months; (6) There are at least 20 remaining teeth in the whole mouth except the third molars, and at least one molar in each section.
Exclusion criteria
Exclusion criteria: (1) have taken antibacterial drugs within 3 months; (2) pregnant women or women of child-bearing age who do not take effective contraceptive measures; (3) systemic diseases such as cardiovascular and endocrine; (4) allergic to penicillin; (5) smokers and those who cannot give up alcohol while taking drugs; (6) do not agree to participate in the test, and do not sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| probing depth;clinical attachment level;bleeding index;plaque index; | — |
Countries
China
Contacts
Peking University School of Stomatology