cervical cancer
Conditions
Interventions
AA:nidaplatin
B:cisplatin
Sponsors
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with cervical cancer diagnosed by pathology for the first time; 2. According to the 2014 FIGO cervical cancer stage, patients with stage IB-IVa; 3. Aged 18 to 70 years; 4. ECOG general condition score 0-2, weight loss = 80 mL / min; (3) Blood function: absolute neutrophil count (ANC) >= 2 x 10^9 / L, platelet count >= 100 x 10^9 / L and hemoglobin >= 9g / dL; (4) Blood sugar level: good blood sugar control, fasting blood glucose 3.9-7.2mmol / L, postprandial blood glucose = 10.0mmol / L, HbA1c < 7% (China Type 2 Diabetes Prevention Guide 2010 edition). 11. The subject agrees and signs the informed consent form (if the subject does not have the ability to judge, the legal guardian is required to sign the informed consent form).
Exclusion criteria
Exclusion criteria: 1. With a serious uncontrollable infection; 2. Factors affecting drug delivery, distribution, metabolism, excretion, etc., such as mental disorders, central nervous system abnormalities, chronic diarrhea, ascites, pleural effusion, etc.; At the same time, receive experimental treatment from other clinical studies (in the treatment period of clinical research or participate in other drug clinical trials within 30 days); 3. Long-term use of immunosuppressants after organ transplantation or combined use of immunopotentiators; 4. There are severe heart, lung, liver and kidney dysfunction such as decompensated heart, lung, kidney, liver and other major organ dysfunction, failure or poor glycemic control, can not tolerate radiotherapy and chemotherapy; 5. Patients with cognitive dysfunction, or who have been judged by the investigator to have poor compliance with radiotherapy and chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematology routine;Adverse effects; | — |
Secondary
| Measure | Time frame |
|---|---|
| local recurrence; | — |
Countries
China
Contacts
Public ContactYang Xiaojing
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Outcome results
None listed