Chronic renal insufficiency
Conditions
Interventions
Group 1:argatroban for lock solution
Group 2:Heparin for lock solution
Sponsors
Dept. of Nephrology,General Hospital of PLA, Beijing
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged older than 18 years male and female; 2. Clinical diagnosis of acute kidney injury/chronic renal failure, receiving hemodialysis treatment; 3. Use temporary or long-term central venous catheters as a blood pathway; 4. Hemodialysis frequency: 3 times/week, 4 hours/time; 5. Signing informed consent.
Exclusion criteria
Exclusion criteria: 1. Receive systemic anticoagulant therapy; 2. Heparin-induced thrombocytopenia or allergies; 3. argatroban allergy; 4. Apply long-term central venous catheters to infect or catheter dysfunction; 5. There is a systemic or local infection at the time of enrollment; 6. Patients with malignant tumors; 7. Pregnancy or breastfeeding; 8. Participating in another clinical researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thrombosis rate;Catheter infection rate; | — |
Countries
China
Contacts
Public ContactXuefeng Sun
Dept. of Nephrology,General Hospital of PLA
Outcome results
None listed