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Multiple Boluses of Oral and IV Tranexamic Acid to Reduce Hidden Blood Loss After primary total hip arthroplasty: A Randomized Clinical Trial

Multiple Boluses of Oral and IV Tranexamic Acid to Reduce Hidden Blood Loss After primary total hip arthroplasty: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017095
Enrollment
Unknown
Registered
2018-07-12
Start date
2018-07-12
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total Hip Arthroplasty

Interventions

A:2g TXA was orally taken 2hbefore operation, and repeated 1g at 3h, 6h and 9h after operation.
B:2g TXA was IV 2h before operation, and repeated 1g at 3h, 6h and 9h after operation.

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: osteoarthritis (OA) or osteonecrosis of the femoral head (ONFH) undergoing unilateral THA

Exclusion criteria

Exclusion criteria: developmental dysplasia of hip, rheumatoid arthritis, revision surgery, a history with thrombosis, patients with infection, allergy to the TXA, uncontrolled hypertension, body mass index (BMI) >35 kg/m2, and preoperative anemia

Design outcomes

Primary

MeasureTime frame
blood loss;range of motion;cost;inflammatory response;—

Countries

China

Contacts

Public ContactYuangang Wu

West China Hospital, Sichuan University

wuyuangang23@163.com+86 18328318171

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026