Pancreatic tumor
Conditions
Interventions
QR Group:Ultrasound-guided QLB using 3mg / kg 0.375% of ropivacaine and intravenous infusion of 0.5 mcg / kg dexmedetomidine
QRM Group:Ultrasound-guided QLB using 3mg / kg 0.375% of ropivacaine+ 0.5 mcg / kg dexmedetomidine and intravenous infusion of 0.5 mcg / kg dexmedetomidine
QNS Group:Ultrasound-guided QLB with 0.8 ml / kg normal saline,and intravenous infusion of 0.5 mcg / kg dexmedetomidine
Sponsors
Department of Anesthesiology, Ruijin Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) aged 18 ~ 65 years old; 2) Patients undergoing upper abdominal surgery scheduled for Chevron incision undergoing general anesthesia with an operative time of 4 to 8 h; 3) ASA classification II ~ III level; 4) BMI = 15.0 to 25.0 kg / m2 [BMI = Body Weight (Kg) / Height (m) 2] (2013 American Guidelines on Management of Overweight and Obese Adults); Ethics, Volunteer Participation, Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1) cognitive dysfunction, communication disorders in patients; 2) patients weighing 10 days or have a history of adrenal cortex suppression or have immune system diseases; 10) hypothyroidism; 11) have a history of asthma; 12) reoperation in 3 months; 13) Contraindications or allergies to test drugs and other narcotic drugs; Patients who participated in other studies within 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma concentration of ropivacaine;VAS and Ramsay Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| patient comfort and satisfaction score;postoperative complication;Time index (call the eyes open time, extubation time, discharge time);score;postoperative agitation;postoperative analgesic pump usage;postoperative complication; | — |
Contacts
Public ContactQingsheng Xue
Department of Anesthesiology, Ruijin Hospital
Outcome results
None listed