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Prognostic value of serum ubiquitin C-terminal hydrolase L1 on the neurological outcome in patients after cardiac arrest: A prospective, multicenter, cohort study

Prognostic value of serum ubiquitin C-terminal hydrolase L1 on the neurological outcome in patients after cardiac arrest: A prospective, multicenter, cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017067
Enrollment
Unknown
Registered
2018-07-10
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neural dysfunction after cardio-pulmonary resuscitation

Interventions

Gold Standard:Cerebral performance category (CPC) score: CPC 1 = good cerebral performance, CPC 2 = moderate cerebral disability
CPC 3 = severe cerebral disability, but conscious
CPC 4 = coma
CPC 5 = death.
Index test:Serum&#32
ubiquitin&#32
C-terminal&#32
hydrolase&#32
L1&#32

Sponsors

General Hospital of Guangzhou Military Command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged ?18 years; 2. Cardiac arrest was defined as receipt of chest compressions for pulselessness by a healthcare worker; 3. Return to spontaneous circulation after cardio-pulmonary resuscitation.

Exclusion criteria

Exclusion criteria: Patients with chronic (such as epilepsy, neural tumor)or acute (such as tramatic brain injury, cerebral hemorrhage) neural organic diseases were excluded.

Design outcomes

Primary

MeasureTime frame
Serum ubiquitin C-terminal hydrolase L1;—

Countries

China

Contacts

Public ContactZhifeng Liu

General Hosipital of Guangzhou Military Command

zhifengliu7797@163.com+86 13711598120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026