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Study on the influnce of Cbfß in human chondrocytes for the pathogenesis of osteoarthritis

Study on the influnce of Cbfß in human chondrocytes for the pathogenesis of osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017066
Enrollment
Unknown
Registered
2018-07-10
Start date
2018-07-01
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Experient group:None
Control group:None
Normal group:None

Sponsors

The Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Accord with diagnostic criteria for osteoarthritis; 2. Aged more than 40 years old.

Exclusion criteria

Exclusion criteria: 1. Chronic consumptive diseases such as tumors and tuberculosis; 2. Other types of bone and joint diseases such as gout and rheumatoid arthritis; 3. Congenital deformity and dysfunction of knee joint caused by congenital factors; 4. People with mental illness can't cooperate with researchers; 5. Menstrual and pregnancy women; 6. With a history of knee joint infection and surgical trauma; 7. With a history of articular cavity puncture and injection therapy; 8. With a history of drugs such as hormone free and immunosuppressive drugs; 9. With serious systemic diseases and no obvious abnormalities in liver, renal function and electrolytes.

Design outcomes

Primary

MeasureTime frame
cbf-ß;

Secondary

MeasureTime frame
Interleukin;TNF-a;MMPs;COMP;YKL-40;CTX-?;ACAN;

Countries

China

Contacts

Public ContactLi Guangdi

The Affiliated Hospital of Guizhou Medical University

leegd@foxmail.com+86 13618585566

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 16, 2026