Scoliosis
Conditions
Interventions
traditional ventilation group, group T:VT=10-12 ml/kg pbw
lung-protective ventilation group, group L:VT=6-8 ml/kg pbw,+PEEP=6-8 cmH2O+RMs
Sponsors
Beijing Children's Hospital, National Center for Children's Health, Capital Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: Aged 1 to 18 years; Scheduled for elective scoliosis surgery; Expected mechanical ventilation duration of = 2 hours; Informed consent has been obtained.
Exclusion criteria
Exclusion criteria: 1. Patients with preoperative respiratory diseases (eg: pulmonary infection such as pneumonia and pulmonary tuberculosis; respiratory allergic diseases such as asthma; pulmonary congenital malformation such as isolated lung and bronchopulmonary dysplasia; space occupying lesion such as thoracic, mediastinal and pulmonary tumor; 2. Obesity, BMI > 35 kg/m2; 3. Progressive neuromuscular disease; 4. Emergency; 5. Refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications, PPCs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Extrapulmonary complications;Unexpected intensive care unit (ICU) admission or readmission;Intensive care unit (ICU) length of stay;Hospital length of stay;all-cause mortality 30 days;Cost; | — |
Countries
China
Contacts
Public ContactJIANMIN ZHANG
Beijing Children's Hospital, National Center for Children's Health, Capital Medical University
Outcome results
None listed