orthopedic surgery
Conditions
Interventions
Group 1:Dexmetomidine
Sponsors
Ningbo 2nd Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. For patients undergoing elective orthopedic surgery without general anesthesia, the duration of surgery is expected to last at least 30min; 2. Aged 18 to 65 years old male and female; 3. BMI 18 kg/m2 to 30 kg/m2; 4. ASA grade I ~ III; 5. The patient has a full understanding of the purpose and significance of this test, and voluntarily participates in this clinical trial, and signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Screening is bradycardia (heart rate or less 50 times/min), III degree atrioventricular block (not including the use of pacemaker patients), and other serious arrhythmia history; 2. Patients with mental system diseases (such as schizophrenia, depression, etc.) and cognitive dysfunction;Patients with a history of epilepsy;Past history of abuse of psychotropic and narcotic drugs; 3. Patients with bronchial asthma; 4. In the first 2 years of randomization, there was a history of drug abuse, drug addiction and alcohol abuse; 5. Artificial 2 receptor agonist or antagonist was used within 14 days before surgery; 6. Abnormal coagulation function; 7. Abnormal liver function; 8. Abnormal kidney function; 9. Allergic to dexmetomidine hydrochloride components or components; 10. Women during pregnancy or lactation; 11. The researchers determined that the patient was not suitable for other conditions of the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ramsay;bispectral index;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactChen Junping
Ningbo 2nd Hospital
Outcome results
None listed