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Correlation study between coagulation factor XII and its gene polymorphism and coronary heart disease

Correlation study between coagulation factor XII and its gene polymorphism and coronary heart disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017006
Enrollment
Unknown
Registered
2018-07-07
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease

Interventions

Patients with luminal constriction more than 50% group:Nil
patients with luminal constriction less than 50% group:Nil

Sponsors

the Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Angiograms were analyzed visually and the degree of stenosis was recorded.coronary heart disease was defined as the presence of visible stenosis with luminal constriction more than 50% in at least one of the coronary arterial segments. Based on visual assessment of the coronary angiograms, patients with luminal constriction less than 50% were included in the control group.

Exclusion criteria

Exclusion criteria: 1) Contrast medium reactions; 2) Severe cardiopulmonary insufficiency; 3) Uncontrolled severe arrhythmia; 4) Uncorrected kaliopenic, digitalism and acid-base imbalance; 5) Severe liver and renal dysfunction Hemorrhagic disease; 6) Hemorrhagic diseases such as bleeding and coagulation dysfunction (Except coagulation factor XII); 7) Who were unwilling to participate the study; 8) Severe infection disease; 9) Others.

Design outcomes

Primary

MeasureTime frame
Plasma coagulation factor XII;Coagulation factor XII gene polymorphism;

Countries

China

Contacts

Public ContactBing Xiao

the Second Hospital of Hebei Medical University

bingxiaocardiology@126.com+86 18631101813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026