Rapid eye movement sleep behavior disorder
Conditions
Interventions
Case series:Nil
Sponsors
Department of Neurology & Institute of Neurology, Ruijin Hospital affiliated with Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) iRBD diagnosised by vPSG; 2) aged between 45 and 75 years old; 3) with verifiable medical history, such as past medical history, family history, etc..
Exclusion criteria
Exclusion criteria: 1) With sign of dementia; 2) With history of intracranial surgery or traumatic brain injury, no psychiatric disorders; 3) With signs of depression, g) no history of severe eye disease (apply to oculomotor examination); 4) With history of other neurological disorders, such as encephalitis, cerebral infarction, etc.; 5) With metal implantation (apply to fMRI examination), not allergic to contrast agents; 6) with no rheumatism history, with no chronic or acute inflammation; 7) With alcoholism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RBD Screening Questionnaire score;Movement Disorders Society Unified Parkinson's Disease rating scale, MDS-UPDRS score;Chinese version of the Mini-Mental State Examination, cMMSE score;Montreal Cognitive Assessment, Moca score;17-item Hamilton Depression Rating Scale, HAMD-17 score;Sniffin Sticks 16-item test, SS-16 score;non motor symptoms questionnaire,NMSQ score;Scale for Outcomes in PD-Autonomic, SCOPA-AUT score;ability of visual tracking;signal value of functional connectivity;ability of upper extremities motor function;ability of gait controlling;uptake of dopamine transporter in basal ganglia;uptake of 18F-FDOPA in basal ganglia;uptake of 18F-FPCIT in basal ganglia; | — |
Countries
China
Contacts
Public ContactJun Liu
Department of Neurology & Institute of Neurology, Ruijin Hospital affiliated with Shanghai Jiao Tong University School of Medicine
Outcome results
None listed