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Multiple Boluses of intravenous Tranexamic Acid to Reduce Blood Loss and inflammatory After primary medial unicompartmental knee arthroplasty: A Randomized Controlled Trial

Multiple Boluses of intravenous Tranexamic Acid to Reduce Blood Loss and inflammatory After primary medial unicompartmental knee arthroplasty: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016961
Enrollment
Unknown
Registered
2018-07-04
Start date
2018-07-05
Completion date
Unknown
Last updated
2018-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unicompartmental knee arthroplasty:

Interventions

A:20mg/kg TXA
B:20mg/kg TXA+1g TXA

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients with osteoarthritis requiring unicompartmental knee arthroplasty; 2. The hemoglobin level of female patients is higher than 120g/L, while that of male patients is higher than 130g/L, which will be included in this standard.

Exclusion criteria

Exclusion criteria: The exclusion criteria were: rheumatoid arthritis, revision surgery, a history with thrombosis, patients with infection, allergy to the TXA, uncontrolled hypertension, body mass index (BMI) >35 kg/m2, and preoperative anemia

Design outcomes

Primary

MeasureTime frame
blood loss;inflammatory;—

Countries

China

Contacts

Public ContactBin Shen

West China Hospital, Sichuan University

wuyuangang23@163.com+86 18980601390

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026