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Multiple of low-dose perioperative dexamethasone improve the clinical outcome after primary medial unicompartmental knee arthroplasty: a randomized controlled study.

Multiple of low-dose perioperative dexamethasone improve the clinical outcome after primary medial unicompartmental knee arthroplasty: a randomized controlled study.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016959
Enrollment
Unknown
Registered
2018-07-04
Start date
2018-07-05
Completion date
Unknown
Last updated
2018-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unicompartmental knee arthroplasty:

Interventions

A:2 doses of normal saline in the anterior vein of skin incision before operation
B:1 dose of 10mg dexamethasone and 1 dose of physiological saline before skin incision
C:2 doses of 10mg dexamethasone in the anterior vein of skin incision before operation

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: All evaluated patients with a diagnosis of osteoarthritis with unicompartmental knee arthroplasty

Exclusion criteria

Exclusion criteria: The exclusion criteria were: rheumatoid arthritis, revision surgery, a history with thrombosis, patients with infection, uncontrolled hypertension, body mass index (BMI) >35 kg/m2, and preoperative anemia

Design outcomes

Primary

MeasureTime frame
blood loss;range of motion;inflammatory;—

Countries

China

Contacts

Public ContactBin Shen

West China Hospital, Sichuan University

wuyuangang23@163.com+86 18980601390

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026