Spinal anesthesia for cesaren section
Conditions
Interventions
norepinephrine group:8ug norepinephrine intravenous bolus
phenylephrine group:100ug phenylephrine intravenous bolus
Sponsors
Department of anesthesiology, Obstetric and Gynecology Hospital Affiliated to Nanjing Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: We enrolled parturients according to the following criteria: ASA I or II, primiparity, singleton, term pregnancy, elective surgery, and scheduled for spinal anesthesia. Eligible subjects were invited to participate in the study immediately after entering into the operating room. All enrolled subjects signed an individual informed consent before spinal anesthesia.
Exclusion criteria
Exclusion criteria: Subjects with one or more of the following characteristics were excluded from the study: younger than 18 or older than 45; weight less than 50kg or more than 100kg; height lower than 140cm or higher than 180cm; multiparous women; twin gestation; suspected compromised fetus; concurrent with preexisting hypertension or pregnancy related hypertension; comorbid with pregnancy related diabetes; comorbid with cardiovascular or cerebrovascular disease; diagnosed as depression or anxiety during pregnancy; occurrence of intraoperative shivering; patients taking monoamine oxidase inhibitors, serotonin reuptake inhibitor, or tricyclic antidepressant; failure in spinal anesthesia. Of note, for those who are not willing to participate in the study, standard obstetric anesthesia and operational procedures were applied as well, however, the corresponding data will not be collected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of hypotension;cardiac strove volume;cardiac output; | — |
Secondary
| Measure | Time frame |
|---|---|
| neonatal Apgar score;neonatal neurobehavioral score;neonatal blood gas analysis; | — |
Countries
China
Contacts
Public ContactShiqin Xu
Obstetric and Gynecology Hospital Affiliated to Nanjing Medical University
Outcome results
None listed