Esophageal Carcinoma
Conditions
Interventions
Case series:Esophageal cancer infusion chemotherapy combined with apatinib
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years old; 2. Patients with advanced esophageal cancer diagnosed by pathological examination, stage II~IV of pathological staging, and patients with advanced esophageal cancer who failed radiotherapy and chemotherapy, have measurable lesions; 3. Life expectancy is expected to exceed 3 months; 4. Eastern Cooperative Oncology Group(ECOG) performance status=1; 5. Pregnancy tests for women of reproductive age must be negative; both men and women should agree to use effective contraception during treatment and within the next year; 6. Subjects with good compliance and followed up voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. INR > 1.5, or underway anticoagulation therapy or known hemorrhagic diseases; 2. unstable coronary heart disease or recent myocardial infarction (within one year); 3. Recent infections required antibiotic treatment; 4. Patients with pulmonary insufficiency (MVV%/VC% = 50% and FVC% = 40%); 5. WBC 2mg/L); 7. AST and/or ALT> 5 ULN; 8. The DSA showed that the tumor blood supply artery contained the anterior spinal artery; the artery was too thin and the intubation was unsuccessful; 9. The comorbidity or social environment that may cause the subject to fail to follow the study plan or even jeopardize patient safety; 10. The patient is accompanied by other primary tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survive;Disease Control Rate;Time To Progress; | — |
Countries
China
Contacts
Public ContactWu Gang
Outcome results
None listed