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The influence of dexmedetomidine on the efficacy of norepinephrine during perioperative period.

The influence of dexmedetomidine on the efficacy of norepinephrine during perioperative period.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016817
Enrollment
Unknown
Registered
2018-06-26
Start date
2018-06-30
Completion date
Unknown
Last updated
2018-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

Group A:Dexmedetomidine0.3µg/kg
Group B:Dexmedetomidine0.5µg/kg

Sponsors

Jinan Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: (1) Voluntary participation in the trial and signing of informed consent instructions; (2) Undergoing elective surgery with tracheal intubation and general anesthesia; (3) ASA I to II; (4) Aged 18-55 years; (5) BMI 18~ 24 kg/m2; (6) Fasted for 8 hours before surgery and no significant body fluid loss.

Exclusion criteria

Exclusion criteria: (1) There is a history of allergies to the studied drug; (2) Preoperative systolic blood pressure = 160 mmHg or diastolic blood pressure = 100 mmHg or mean arterial pressure = 90 mmHg; (3) Participants had nervous system, cardiovascular system, endocrine system and abnormal liver and kidney function; (4) Disturbance of water, electrolyte and acid-base balance; (5) Anemia (hemoglobin = 90 g/L).

Design outcomes

Primary

MeasureTime frame
Use dose of norepinephrine;Noradrenaline use duration;

Secondary

MeasureTime frame
blood pressure;Heart rate;

Countries

China

Contacts

Public ContactJie Ren

Jinan Central Hospital

jijie-ren@sohu.com+86 13370582090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026