none
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Voluntary participation in the trial and signing of informed consent instructions; (2) Undergoing elective surgery with tracheal intubation and general anesthesia; (3) ASA I to II; (4) Aged 18-55 years; (5) BMI 18~ 24 kg/m2; (6) Fasted for 8 hours before surgery and no significant body fluid loss.
Exclusion criteria
Exclusion criteria: (1) There is a history of allergies to the studied drug; (2) Preoperative systolic blood pressure = 160 mmHg or diastolic blood pressure = 100 mmHg or mean arterial pressure = 90 mmHg; (3) Participants had nervous system, cardiovascular system, endocrine system and abnormal liver and kidney function; (4) Disturbance of water, electrolyte and acid-base balance; (5) Anemia (hemoglobin = 90 g/L).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Use dose of norepinephrine;Noradrenaline use duration; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;Heart rate; | — |
Countries
China
Contacts
Jinan Central Hospital