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Study on Metabolomic Mechanism of IVF Outcome of TCM Patients with Shen Yang Deficiency PCOS: Prospective, Randomized, Controlled, Double-Blind Trial

Study on Metabolomic Mechanism of IVF Outcome of TCM Patients with Shen Yang Deficiency PCOS: Prospective, Randomized, Controlled, Double-Blind Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016792
Enrollment
Unknown
Registered
2018-06-24
Start date
2018-07-01
Completion date
Unknown
Last updated
2018-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Interventions

Experimental group:Yougui capsule
Control group:Placebo

Sponsors

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Non-pregnant and lactating women younger than 35 years of age; 2. Western diagnosis is consistent with polycystic ovary syndrome (PCOS); 3. dialectical Chinese medicine meets the kidney-yang deficiency syndrome; 4. No ovulation therapy was used in the past 3 months, and there was no contraceptive therapy for ovulation therapy; 5. gynecological examination without organic disease; 6. No other obvious gynecological diseases, normal liver and kidney function; 7. non-immune diseases; 8. Signed informed consent to receive regular follow-up.

Exclusion criteria

Exclusion criteria: 1. abnormalities in the development of congenital genital organs and congenital diseases, resulting in abnormal reproductive organs; 2. Combined diseases such as liver and kidney dysfunction, cardiovascular disease, hematopoietic system diseases, abnormal thyroid and adrenal function, severe mental disorders, etc.; 3. Those who are allergic to the drug or severe allergies to this clinical trial; 4. taking any hormone drugs and other drugs that affect reproductive endocrine within the last 3 months; 5. Patients who participated in other drug clinical trials; 6. Patients who fail to take prescribed medications and cannot complete statistics on their cases.

Design outcomes

Primary

MeasureTime frame
Follicular fluid metabolites;Obtained egg rate;High-quality egg rate;fertilization rate;good quality embryo rate;Implantation rate;Clinical pregnancy rate;Onging pregnancy rate;Abortion rate;Syndrome points;Hormone levels;

Countries

China

Contacts

Public ContactZhengao Sun

Shandong University of Traditional Chinese Medicine

sunzhengao77@163.com+86 13708938621

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026