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A randomized, single blind, controlled trial for the effect of quadriceps muscle strength training in the treatment of knee crepitus and knee joint pain

A randomized, single blind, controlled trial for the effect of quadriceps muscle strength training in the treatment of knee crepitus and knee joint pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016775
Enrollment
Unknown
Registered
2018-06-23
Start date
2018-06-26
Completion date
Unknown
Last updated
2018-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee arthritis

Interventions

Train group:quadriceps muscle strength training
Control group:NSAIDs medication

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. aged 30-70 years old; 2. knee joint pain, upstair or downstair or squat VAS>4, walk on flat VAS<4, rest pain VAS<1; 3. primary knee OA, Course of the disease =1 month; 4. no knee joint injection in recent 1 month, no knee surgery history; 5. radiograph and/or physical examination evidenced that knee joint pain and daily activity limitations caused by knee OA.

Exclusion criteria

Exclusion criteria: 1. secondary knee joint arthritis: Rheumatoid arthritis, traumatic arthritis, Chacot's joints, etc.; 2. mild knee joint pain, Course of the disease 4; 4. Pathological fractures (vertebral metastases, myeloma, etc.); 5. accompanied by Parkinson's disease, cerebral infarction and other nervous system basic diseases; 6. radiograph and/or physical examination evidenced that knee joint pain and daily activity limitations not caused by knee OA; 7. accompanied by malignant diseases or other systemic diseases that seriously affect the activity, function and quality of life.

Design outcomes

Primary

MeasureTime frame
knee pain assessment;OKS;Knee joint friction vibration signal;quadriceps muscle strength;

Secondary

MeasureTime frame
knee ROM;

Countries

China

Contacts

Public ContactWu Peihui

The First Affiliated Hospital of Sun Yat-sen University

wupeihui@mail2.sysu.edu.cn+86 13332807351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026