poliomyelitis
Conditions
Interventions
Group 1:1st dose of IPV manufactured by Pasteur at the age of 2 months, 2nd and 3rd dose of IPV manufactured by Beijing Bio-Institute Biological Products at the age of 3 and 4 months respectively
Group 2:1st, 2nd and 3rd dose of IPV manufactured by Pasteur at the age of 2, 3 and 4 months, respectively
Sponsors
Beijing Center for Diseases Prevention and Control
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subjects aged more than 2 months on the day of enrollment; 2. Subjects parent(s)/legal guardian(s) are able to understand and sign informed consents with date; 3. guardians are able to participate in all follow-up visits and agree to comply all research procedures; 4. not less than 14 days after the last vaccination; 5. make sure body temperature is no more than 37.0 degree C.
Exclusion criteria
Exclusion criteria: (1) Allergic to the vaccine's active substance , any inactive substance or material used in preparation processes, or allergic to the vaccine; (2) Have serious chronic diseases or allergies; (3) Have a fever or acute illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| poliovirus type I, II, III seroconversion rate;poliovirus type I, II, III antibody level (GMT); | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactWu Jiang
Outcome results
None listed