Acute upper respiratory tract infection (acute tonsillitis, acute pharyngitis,etc.)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. diagnosis as acute upper respiratory tract infectionacute in children such as tonsillitis, acute pharyngitis; 2.Outpatients or emergency patients aged 1-14 years old(including 1-year old and 14-year old); 3. duration of disease within 48h; 4. treated with Nauclea officinalis Extract syrup or Zhiqiao Qingre granule.
Exclusion criteria
Exclusion criteria: 1. diagnose as purulent tonsillitis, bronchitis, bronchiolitis, pneumonia and other lower respiratory tract infections, influenza or influenza-like cases; 2. Children consider as bacterial infection with white blood cell (WBC)> 1.2 times reference value upper limit (ULN) or the absolute value of neutrophils (N) > ULN; 3. Children have history of epilepsy and recurrent respiratory infection; 4. Children with severe malnutrition, rickets, diabetes, congenital heart disease.or other severe systemic diseases such as brain, liver, kidney and hematopoietic system; 5. Children who are allergic to drugs; 6. Antiviral or similar drugs have been used before treatment; 7. According to the researcher's judgment, children who are easy to lost to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recovery time of Major symptoms complete remission; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major symptoms relief time;time to defervescence;admission rate;medication compliance; | — |
Countries
China
Contacts
West China Second University Hospital, Sichuan University