spinal metastatic tumor
Conditions
Interventions
SR group:Separation surgery followed by radiotherapy
TES group:total enbloc spondylectomy
Sponsors
Department of Orthopedic Oncology, Changzheng Hospital, Navy Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. patients diagnosed with spinal metastatic tumor, with solitary spinal lesion or with certain responsible vertebrae in multiple-level spinal metastases; 2. Aged over 18 years; 3. life expectancy longer than 6 months; 4. patients with neurological deficits or spinal instability (SINS=6); 5. inform consent form signed
Exclusion criteria
Exclusion criteria: 1. primary spianl tumor; 2. patients with uncertain responsible vertebrae in multiple-level spinal metastases; 3. patients receiving revision of spinal tumor; 4. patients with poor general conditions, and those who are intolerance of operation, radiotherapy, chemotherapy and target therapy; 5. patients participating other RCTs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progression-free survival;overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frankel Score;VAS score;quality of life; | — |
Countries
China
Contacts
Public ContactJianru Xiao
Department of Orthopedic Oncology, Changzheng Hospital, Navy Medical University
Outcome results
None listed