postoperative pulmonary complications
Conditions
Interventions
General anesthesia group:Opioid drugs
No opiate drug anesthesia group:No opioids
Sponsors
Chengdu Military General Hospital
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients undergoing elective radical resection of esophageal cancer; they were older than 45 years with an American Society of Anesthesiologists status score from I to III. Extubation of trachea catheter after operation, patients who need postoperative analgesia and volunteered to participate in the study.
Exclusion criteria
Exclusion criteria: Patients with contraindication of epidural anesthesia (such as hypersensitivity reaction to local anesthetic, coagulation disorders, and systemic or local infection); hypersensitivity reaction to general anaesthetic; a central nervous system disease, mental illness; without normal speech communication; cardiac function III to IV, a pacemaker, liver and kidney failure, severe preoperative lung function damage and need respiratory support after operation; intraoperative blood loss greater than 20% of blood volume and those who need secondary reoperation after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications, include Pneumonia, atelectasis, pleural effusion, respiratory failure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions: respiratory depression, nausea score, vomiting score, dizziness, fatigue, urinary retention, pruritus;Postoperative analgesia score (visual analogue scale VAS), sedation score (modified OAA / S score);Cognitive assessment;operation time;Extubation time;Postoperative hospital days;Hospital costs;Hemodynamic parameters (SBP, DBP, MAP, HR, SPO2);Patient satisfaction; | — |
Countries
China
Contacts
Public ContactWei Wu
Department of Anesthesiology, Chengdu Military General Hospital
Outcome results
None listed