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Efficacy of Dexmedetomidine on Postoperative Pain and Recovery in Patients Undergoing Tangential Excision Skin Grafting

Efficacy of Dexmedetomidine on Postoperative Pain and Recovery in Patients Undergoing Tangential Excision Skin Grafting

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016646
Enrollment
Unknown
Registered
2018-06-14
Start date
2018-06-14
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tangential Excision Skin Grafting

Interventions

The DEX group :Group D received intravenous single-dose bolus injection of DEX 0.5 ug/kg over10 minutes before induction of anesthesia.PCIA was given to patients at the end of the surgery, which cont
The control group :Group C received volume-matched normal saline and 100 ug sufentanil infusion.

Sponsors

Yantai Yuhuangding Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: We enrolled 60 consecutive patients, aged 18 - 65 yr, ASA grade II or III, burn surface area met moderate to severe burn criteria, conscious and active cooperation, who underwent general anesthesia for tangential excision skin grafting.

Exclusion criteria

Exclusion criteria: known or suspected allergy to alpha-2 receptor agonist or nonsteroidal anti-inflammatory drugs; sinus bradycardia; myocardial dysfunction; chronic respiratory insufficiency; impaired renal or hepatic function; regular use of sedatives, antidepressants; combined with respiratory burn and severe complex injuries.

Design outcomes

Primary

MeasureTime frame
resting VAS pain score;VAS score after exercise;The QoR-40 score;

Countries

China

Contacts

Public ContactMa Jiahai

Yantai Yuhuangding Hospital

mjh-214@126.com+86 13656456186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 22, 2026