mechanical ventilation
Conditions
Interventions
experimental group :an electroencephalograph-based objective monitoring
control group:no
Sponsors
Daxing Teaching Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Adult patients were eligible for inclusion if they were intubated and ventilated within the previous 24 hours, were administered with continuous or intermittent intravenous sedatives and/or analgesics, and were expected to receive mechanical ventilation and sedation for longer than 24 hours.
Exclusion criteria
Exclusion criteria: 1) age under 18 or over 65 years; 2) continuously infusion of muscle relaxants; 3) diagnosed or suspected brain diseases, which including brain trauma, intracranial hemorrhage, stroke, brain tumors, hypoxic-ischemic encephalopathy, epilepsy and meningitis; and 4) diagnosed conditions that resulted in a decrease level of consciousness apart from sedation and analgesia, which including hypoxemia with partial pressure of oxygen in arterial blood less than 60 mmHg, hypotension with systolic blood pressure less than 90 mmHg, hypoglycemia with blood glucose concentration less than 4.1 mmol/L, anemia with hemoglobin concentration less than 70 g/L, and body temperature below 36 degree C.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation depth; | — |
Countries
China
Contacts
Public ContactJian-Xin Zhou
Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed