Impact of Maternal Glycolipid Metabolism in Early Pregnancy on Congenital Heart Disease in Offspring and Its Related Mechanisms

Conditions

congenital heart diseases

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10.1186/s13052-025-02080-x

Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population

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Journal of Health Population and Nutrition2024-12-19

10.1186/s41043-024-00699-w

Maternal anaemia during early pregnancy and the risk of neonatal outcomes: a prospective cohort study in Central China

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BMJ Paediatrics Open2024-01-0112 citations

10.1136/bmjpo-2023-001931

Association of MTR gene polymorphisms with the occurrence of non-syndromic congenital heart disease: a case-control study.

Liu Y, Zhong T, Song X, Zhang S, Sun M, Wei J, Shu J, Yang T, Wang T, Qin J.

2023-06-094 citations

10.1038/s41598-023-36330-x

Association of methylenetetrahydrofolate reductase gene polymorphisms and maternal folic acid use with the risk of congenital heart disease

Taowei Zhong, Xinli Song, Yiping Liu, Mengting Sun, Senmao Zhang et al. (14 authors)

Frontiers in Pediatrics2022-09-088 citations

10.3389/fped.2022.939119

Association Between First-Trimester Maternal Cytomegalovirus Infection and Stillbirth: A Prospective Cohort Study

Xinli Song, Qiongxuan Li, Jingyi Diao, Jinqi Li, Yihuan Li et al. (14 authors)

Frontiers in Pediatrics2022-03-177 citations

10.3389/fped.2022.803568

Association of Maternal Dietary Habits and MTHFD1 Gene Polymorphisms With Ventricular Septal Defects in Offspring: A Case-Control Study

Xinli Song, Yiping Liu, Tingting Wang, Senmao Zhang, Mengting Sun et al. (13 authors)

Frontiers in Pediatrics2022-02-025 citations

10.3389/fped.2021.785440

Association of MTHFD1 gene polymorphisms and maternal smoking with risk of congenital heart disease: a hospital-based case-control study.

Song X, Li Q, Diao J, Li J, Li Y, Zhang S, Zhao L, Chen L, Wei J, Shu J, Liu Y, Sun M, Huang P, Wang T, Qin J.

2022-01-319 citations

10.1186/s12884-022-04419-2

Interventions

exposure group:not applicable

Non-exposed group:not applicable

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women in early pregnancy; 2. Pregnant women who agreed to participate in the study; 3. pregnant women who completed the whole research process, and the outcome index diagnosis is clear.

Exclusion criteria

Exclusion criteria: 1. Pregnant women who did not agree to participate in the study; 2. Pregnant women with severe disorders such as mental disorders; 3. Lost visitor.

Design outcomes

Primary

Measure	Time frame
Glucose and Lipid Metabolism Indexes of mothers in early pregnancy;Fetal Cardiac specific transcription Factor Gene Polymorphism;Diagnosis of congenital heart disease;	—

Countries

China

Contacts

Public ContactJiabi Qin

Xiangya School of Public Health, Central South University

qinjiabi123@163.com+86 15974269544

Outcome results

None listed