femoral trochanteric fractures
Conditions
Interventions
control group:NO
tranexamic acid group: intravenous tranexamic acid
Sponsors
Beijing Jishuitan Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. aged =65 years old; 2. femoral trochanteric fracture(including intertrochanteric fracture and subtrochanteric fracture, AO classification 31A).
Exclusion criteria
Exclusion criteria: 1. Contraindication or allergy to tranexamic acid (e.g previous arterial or venous thrombosis, renal dysfunction( glomerular filtration rate<30), previous seizure); 2. Delayed admission beyond 24h; 3. Acquired disturbances of color vision; 4. Pathological fracture due to metastatic tumor; 5. Peri-prosthetic fracture; 6. Acute myocardial infarction in 6 months( unstable angina is not included); 7. Cerebrovascular diseases in 6 months( e.g cerebral infarction, cerebral hemorrhage, but transient ischemic attack(TIA) is not included); 8. Thrombophilia( e.g end stage of malignancy, Disseminated intravascular coagulation(DIC), severe hyperlipidemia, glucocorticoid replacement therapy); 9. Other patients whom researchers consider inappropriate for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean blood transfusion;Mean blood transfusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative hidden blood loss; | — |
Countries
China
Contacts
Public ContactZhu Shiwen
Beijing Jishuitan Hospital
Outcome results
None listed