ALS, amyotrophic lateral sclerosis
Conditions
Interventions
Group 1:Abbott Ensure Complete
Group 2:Megestrol
Sponsors
Dahua Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Participants diagnosed as familial or sporadic ALS, according to the World Federation of Neurology Standards; (2) male or female participants aged 18-70 years; (3) Participants must be able to provide informed consent and follow the test procedure; (4) Participants must have qualified nursing staff to assist in tube feeding; (5) The participants receiving the gastric fistula or stoma tube must be able to receive tube feeding; (6) The subjects were able to carry out non-invasive ventilation for less than 10 hours a day.
Exclusion criteria
Exclusion criteria: (1) Patients with unstable mental illness, including mental depression; (2) Women during pregnancy and who breastfeed after pregnancy; (3) History of hepatitis, including Nonalcoholic steatohepatitis (NASH), cholecystectomy, previous biliary diseases such as gallstones, diabetes, previous myocardial infarction, stroke and thromboembolism, liver and kidney insufficiency, breast tumor, uterine fibroids, hypertension, galactose or hyperglycemia patients; (4) Laboratory examination value: Alanine transaminase (ALT) or aspartate transaminase (AST) is greater than the normal range of 2.2 times or total bilirubin greater than the normal limit of twice times; (5) allergic to soybeans, fish or dairy products; (6) intolerance of nutritional supplements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRNA expression; | — |
Countries
China
Contacts
Public ContactCAO JUN
Dahua Hospital
Outcome results
None listed