Ossification of Posterior Longitudinal Ligament ( OPLL )
Conditions
Interventions
Group A:Underwent Posterior Laminoplasty
Group B:Underwent Posterior Laminectomy
Group C:Underwent Posterior Laminectomy with Fixation
Sponsors
Changzheng Hospital, Second Militray Medical University
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) patients aged 18-65 years, without gender limitation, are willing to sign informed consent; 2) patients diagnosed with OPLL,CT showed that the compression of the posterior longitudinal ligament ossification involve more than 3 spinal segments; 3) patients presented with limbs numbness, walking instability, or other spinal cord, nerve root compression symptoms, which may be associated with OPLL;4)Conservative treatment is invalid.
Exclusion criteria
Exclusion criteria: 1) Cervical ligamentous ossification, cervical trauma, cervical cancer, cervical tuberculosis and other inflammatory diseases; 2) accompanied by other spine parts of the disease affect the clinical symptoms of patients; 3) associated with amyotrophic lateral sclerosis and other motor neuron diseases and other neurological diseases; 4) poor health condition, unable to tolerate surgery; 5) patients (or their guardians) can not give full informed consent for adult dysfunction; 6) patients who have participated in other clinical trials in the past 1 month; 7) patients with active hepatitis B (including HBeAg) or serological markers (HBsAg or / and HBeAg or / and HBcAb), hepatitis C, tuberculosis, cytomegalovirus infection, severe fungal infection, HIV infection or patients with Turmor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JOA score;shift of posterior margin of the spinal cord; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neck disability index;visual analogue scale(VAS);curvature index (CI);Incidence rate of C5 root palsy;time of operation; | — |
Countries
China
Contacts
Public ContactGuohua Xu
Department of Orthopaedic Surgery, The spine surgical center, Changzheng Hospital, Second Militray Medical University
Outcome results
None listed