Tourniquet related hypertension
Conditions
Interventions
Group M:patients in the magnesium group(M
n=30) will receive intraveous magnesium sulphate 30mg/kg within 10 minutes followed by 15mg/kg/h via a infusion pump until the end of tourniquet inflation
Group C:Patients in the control group(C
n=30) received the same volume of normal saline infused over the same period
Sponsors
Anesthesiology Department, Xuzhou Medical University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: A total of 60 patients aged 18-70 years, ASA grade I-II, who scheduled for elective unilateral lower extremity surgery requiring tourniquet inflation
Exclusion criteria
Exclusion criteria: (1) Patients are allergic to magnesium sulphate or other drugs used in the present study; (2) Patients have liver and/or kidney dysfunction; (3) Patients have severe arrhythmia, cardiac insufficiency, nomuscular disease or electrolyte imbalance; (4) Patients have uncontrolled hypertension(SBP>160mmHg and/or DBP>90mmHg); (5) Time of tourniquet inflation is more than 90 minutes or less than 60 minutes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure; | — |
Countries
China
Contacts
Public ContactYAN Ming
Xuzhou Medical University Affiliated Hospital
Outcome results
None listed