Anesthesia of awake craniotomy
Conditions
Interventions
Group A:Nasal oxygen flow rate 20L/min
Group B:Nasal oxygen flow rate 40L/min
Group C:Place the tube between epiglottis and vocal cords through nasal cavity
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
14 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Patients aged 14-70 years(gender is not limited) 2) planning to receive the elective neurosurgery of awake craniotomy in the brain function area or epilepsy area ; 3) ASA I~II; 4) No aphasia or myodynamia changes were observed before surgery; 5) Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. There is a serious system disease and it is in the period of decompensation (such as severe medical complications) : 1) cardiac function = grade 3; 2) respiratory failure; 3) hepatic and renal insufficiency; 4) diseases of the blood system; 5) uncontrolled hypertension; 6) patients with a history of COPD and pulmonary fibrosis, who smoked heavily for a long time before surgery; 7) patients with severe intracranial hypertension and cerebral hernia before surgery; 2. extreme anxiety and fear of surgery, and it is estimated that it is difficult to cooperate in surgery; 3. patients with preoperative consciousness and cognitive dysfunction; 4. preoperative communication disorder, aphasia; 5. patients with pathological obesity (BMI greater than 30) and obstructive sleep apnea syndrome; 6. patients with difficulty to intubation in clinical evaluation; 7. patients with glioma combined with other systemic tumors; 8. female pregnancy; 9. participated in other clinical trials in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intracranial pressure;PaCO2;PaO2;SpO2;OAA/S score;BIS; | — |
Countries
China
Contacts
Public ContactGU HUAHUA
Huashan Hospital, Fudan University
Outcome results
None listed