Irreducible Atlantoaxial Dislocation
Conditions
Interventions
Direct posterior comprehensive reduction approach surgery Group:Underwent Direct posterior comprehensive reduction approach surgery
Traditional Ocipitocervical fusion surgery Group:Underwent Traditional Ocipitocervical fusion surgery
Posterior reduction combined with anterior release of the cervicomedullary junction:Anterior approach was used routinely to release the cervicomedullary junction before posterior fusion and stabilizat
Sponsors
Changzheng Hospital, Second Militrary Medical University
Eligibility
Sex/Gender
All
Age
10 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) patients aged 10-70 years, without gender limitation, are willing to sign informed consent; 2) patients diagnosed with irreducible atlantoaxial dislocation; 3) patients with limbs numbness, walking instability, or other spinal cord, nerve root compression symptoms, may be associated with irreducible atlantoaxial dislocation, conservative treatment is invalid or gradually increased; 4) There was no significant reduction in atlantoaxial dislocation after 1-3 weeks of preoperative traction.
Exclusion criteria
Exclusion criteria: 1) Cervical ligamentous ossification, cervical trauma, cervical cancer, cervical tuberculosis and other inflammatory diseases; 2) accompanied by other spine parts of the disease affect the clinical symptoms of patients; 3) associated with amyotrophic lateral sclerosis and other motor neuron diseases and other neurological diseases; 4) poor health condition, unable to tolerate surgery; 5) patients (or their guardians) can not give full informed consent for adult dysfunction; 6) patients who have participated in other clinical trials in the past 1 month; 7) patients with active hepatitis B (including HBeAg) or serological markers (HBsAg or/and HBeAg or/and HBcAb), hepatitis C, tuberculosis, cytomegalovirus infection, severe fungal infection , HIV infection or patients with Turmor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| JOA score; | — |
Secondary
| Measure | Time frame |
|---|---|
| NURIC;Visual Analogue Scale/Score(VAS);Radiological parameters; | — |
Countries
China
Contacts
Public ContactGuohua Xu
Department of Orthopaedic Surgery, The spine surgical center, Changzheng Hospital, Second Militrary Medical University
Outcome results
None listed