cerebral palsy
Conditions
Interventions
hUC-MSCs group:hUC-MSCs+ rehabilitation
Control group:0.9% NS containing 1% human albumin+ rehabilitation
Sponsors
Affiliated Taihe Hospital of Hubei University of Medicine
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 2 and 12. 2.Diagnosed as CP (a)Motor disorder caused by insult to the central nervous system; (b)Non-progressive brain injury; (c)Delayed developmental presentation in infancy; (d)Could be associated with additional developmental disabilities, such as cognitive impairment, epilepsy, sense and consciousness disorder, and so on; (e)Ruled out the motor defect causing by other progressive diseases and the transient delayed motor milestone in normal cases. 3.Signed informed consent forms showing their willingnes 4.Was able to comply with all the study procedures, including but not limited to treatment schedule, examination plans, and performance scales evaluation.
Exclusion criteria
Exclusion criteria: 1.Previous history of epilepsia gravior within 15 days of infusion and seizures attack within 24 hours of treatment. 2.Congenital cardiopathy. 3.Any known genetic or immunological disease, or coagulation disorder, or serious liver or renal dysfunction; 4.Malignancy history. 5.Serious allergy history or known allergy to more than 2 kinds of food or medications. 6.Active serious infection. 7.Participating in other clinical trials within 3 months of screening. 8.Any other concerns that hampered the compliance or safety judging by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gross motor function measure (GMFM);Comprehensive function assessment (CFA);Activities of daily living (ADL); | — |
Countries
China
Contacts
Public ContactGu Jiaowei
Affiliated Taihe Hospital of Hubei University of Medicine
Outcome results
None listed