cancer related depression
Conditions
Interventions
real acupuncture:acupucnture
sham acupuncture:skin-touch needle
Healthy control:will not receive any intervention
Sponsors
Guangdong Provincal hospital of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients with primary breast malignancy diagnosed pathologically or cytologically; (2) Meet diagnostic criteria for depression disorders (Diagnostic criteria for mental disorders in the United States (DSM-IV)), and the HAMD-17 questionnaire> 7 points and = 24 points. Patients with 5 of the following 9 symptoms lasted for at least 2 weeks and excluded history of depression, suicide and mania, family history of psychosis and sedative-hypnotics, steroids, and contraceptives currently used to cause depressive symptoms. Drugs, etc., can basically establish the diagnosis. 9 symptoms include: depressed; lack of interest; weight loss or increase; insomnia or excessive sleep; irritation or slow movement; fatigue or loss of energy; self-evaluation is too low or have guilt; Difficulties in focusing attention; thoughts about wanting to die or commit suicide (previously no history of mental illness); (3) The original underlying disease (if any) has a stable condition, such as good control of blood sugar and blood pressure, and does not affect the treatment of breast cancer; (4) had undergone mastectomy or partial resection, no distant metastatic lesions were found; or only a single visceral metastatic lesion (except intracranial metastases) and no evidence of disease progression was found within the last 6 months; (5) The patient is allowed to incorporate other drugs (such as endocrine drugs, antihypertensive drugs, etc.) during treatment, but the protocol cannot be changed or adjusted during the 2 weeks before treatment and during treatment; (6) Aged 18 to 75 years old, who has full civil capacity, volunteers to participate in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. At the same time, there are serious or poorly controlled medical conditions (such as systemic lupus erythematosus, cirrhosis, etc.), or serious tumor complications and complications (such as oppressive jaundice, ascites, portal hypertension, etc.), Or with intracranial metastases; 2. Have been diagnosed with depression or other mental illness, whether recovered or not; 3. For any reason, life expectancy is less than 1 year; 4. Pregnancy, lactation women; 5. are participating in other clinical trials; 6. Failure to attend the clinic on time, poor adherence or inability to adhere to the follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-17;Sleep monitoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| PSQI;FACT-B; | — |
Countries
China
Contacts
Public ContactWenbin Fu
Department of Acupuncture and Moxibusti second affiliated hospital of Guangzhou University of Chines Medicine
Outcome results
None listed