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Regulating express of BMP7 through miRNA-542-3p to control EMT for Heterotopic ossification therapy

Regulating express of BMP7 through miRNA-542-3p to control EMT for Heterotopic ossification therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800016542
Enrollment
Unknown
Registered
2018-06-07
Start date
2018-07-01
Completion date
Unknown
Last updated
2018-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heterotopic ossification

Interventions

2:non

Sponsors

Sixth People's Hospital Affiliated to Shanghai Jiao Tong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Randomly selected patients with ectopic ossification in our hospital were divided into heterotopic ossification group and normal tissue control group according to the specimens of heterotopic ossification and normal muscle tissue specimens.

Exclusion criteria

Exclusion criteria: (1) combined with diabetes, hyperthyroidism, hyperparathyroidism, and other endocrine diseases that affect bone metabolism; (2) combined with liver and kidney dysfunction, gastritis, enteritis, rheumatoid arthritis or bone tumors and other malignant tumors; (3) those who had undergone radiotherapy for heterotopic ossification and those who had used hormones or other drugs that affect bone metabolism; (4) fractures within a year may result in limited motor function.

Design outcomes

Primary

MeasureTime frame
miRNA;—

Countries

China

Contacts

Public ContactBIAO ZHONG

Sixth People's Hospital Affiliated to Shanghai Jiao Tong University

biao_zhong@163.com+86 18930177319

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026