thyroid associated ophthalmopathy
Conditions
Interventions
active thyroid associated ophthalmopathy:evaluation of the ocular surface status
inactive thyroid associated ophthalmopathy:evaluation of the ocular surface status
normal subjects:evaluation of the ocular surface status
Sponsors
Changzheng Hospital, Second Military Medical University
Eligibility
Sex/Gender
All
Age
27 Years to 56 Years
Inclusion criteria
Inclusion criteria: (1) Normal subjects; (2) Patients diagnosed as thyroid associated ophthalmopathy.
Exclusion criteria
Exclusion criteria: 1) age less than 18 years or more than 80 years old; 2) pregnant women and breast-feeding women; 3) with the history of systemic and inflammatory diseases 4) systemic or topical glucocorticoids or immunosuppressive agents were used within 6 months; 5) the history of anterior segment diseases such as dry eye, conjunctivitis, meibomian gland dysfunction, allergic eye disease, pterygium, corneal dystrophy, uveitis, and the use of eye drops within 3 months; 6) the history of ocular trauma and the history of ocular surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| corneal sensitivity;ocular surface disease index;tear film break up time;corneal fluorescein staining;Schirmer test;Corneal nerve fiber density;Corneal nerve branch density;Corneal nerve fiber length;Corneal nerve fiber total branch density;Corneal nerve fiber area;Corneal nerve fiber width;Corneal nerve fiber fractal dimension; | — |
Secondary
| Measure | Time frame |
|---|---|
| free triiodothyronine;free thyroxine;thyroid stimulating hormone; | — |
Countries
China
Contacts
Public ContactWu Lianqun
Changzheng Hospital, Second Military Medical University
Outcome results
None listed