clinical anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Experimental group: Children who were under general anesthesia and had stable intraoperative vital signs during the period from January 2008 to December 2012 (within 2 years of age). Control group: Normal children of the same age who had not experienced surgery and anesthesia within the age of 2 years and the rest criteria were the same as the experimental group.Both groups signed written informed consent.
Exclusion criteria
Exclusion criteria: (1) Parents refuse to participate in this study; (2) Abnormal maternal pregnancy: including mothers diagnosed with moderate-to-severe high-pregnancy hypertension, severe gestational diabetes, moderate-to-severe gestational anemia, and poor contact (rays, medications, heavy metals, etc.); (3) Perinatal abnormalities or complications: including premature birth, low birth weight, neonatal asphyxia (Apgar score =7 points at 1 or 5 minutes after birth), postpartum neonatal ICU, and delivery-related head complications Symptoms (including neonatal head hematoma, intracranial hematoma, intraventricular hemorrhage, etc.), neonatal pathological jaundice, etc.; (4) Congenital malformations: including congenital heart disease, hydrocephalus, spina bifida, etc.; (5) Acquired diseases that affect mental development: including mental disorders such as central nervous system infections, trauma history, epilepsy, and schizophrenia; (6) There are intellectual disabilities, schizophrenia, manic depressive psychosis, etc. in family history; (7) Loss of contact, eviction or death.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WISC-1V, full scale IQ;WISC-1V, different cognitive dimensions; | — |
Secondary
| Measure | Time frame |
|---|---|
| IVA-CPT;SNAP-?;Child Behavior Check List, CBCL;Sensory Integration Theory;Japanese S-M social life ability scale; | — |
Countries
China
Contacts
Children's Hospital of Nanjing Medical University