Acute myeloid leukemia
Conditions
Interventions
Reinduction:Dec+HA
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years and older; 2. patients diagnosed with MDS were not treated with DTA; 3. IPSS-R classification was low or intermaediate risk; 4. appropriate cardiac function (QTc interval is less than 460 milliseconds); 5. the function of liver and kidney: creatinine less than 2 mg/dl, total bilirubin less than 2 mg/dl, cereal transaminase (AST) less than 2.5 times the normal upper limit (ULN), alanine aminotransferase (ALT) less than 2.5 ULN; 6. sign informed consent.
Exclusion criteria
Exclusion criteria: 1. pregnant women or lactation women; 2. patients with uncontrolled heart failure, unstable angina, arrhythmia or mental disorders; 3. uncontrolled infection disease; 4. HIV infected patients; 5. Patients with 3 or high stage chronic renal disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| remission state of bone marrow;remission state of hematology;disappear of extramedullary invasion;event-free survival;overall survival;cumulative disease rate of relapse; | — |
Secondary
| Measure | Time frame |
|---|---|
| early mortality rate; | — |
Countries
China
Contacts
Public ContactLi Wang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed