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Comparison of TIVA with a balanced anesthesia using propofol and low concentration sevoflurane: A BIS guided study

Comparison of total intravenous anesthesia versus a propofol target controlled infusion combined with low MAC sevoflurane

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016517
Enrollment
Unknown
Registered
2018-06-06
Start date
2016-08-08
Completion date
Unknown
Last updated
2018-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthetic effects on cardiovascular, neuromuscular and central nervous systems.

Interventions

P:Control
PS1:propofol + sevoflurane 1%
PS2:propofol + sevoflurane 1.5%

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged 20-65 years, with American Society of Anesthesiologists (ASA) I-II physical status, BMI < 30 kg/m2 and due for elective abdominal, gynecological and lower limb surgeries under general anesthesia

Exclusion criteria

Exclusion criteria: Uncontrolled hypertension, diabetes, endocrinal disorders, neurological; Disorders including epilepsy, hepatic and renal impairment, neuromuscular disorders, BMI >30kg/m2, History of allergy, pregnant patients, patients on drugs which interfere with neuromuscular relaxants as anticonvulsants and aminoglycosides.

Design outcomes

Primary

MeasureTime frame
Safety;—

Countries

China

Contacts

Public ContactProfessor Wang Guolin

Tianjin Medical University General Hospital

wang_guolin@hotmail.com+86 158 2285 5556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026