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Clinical efficacy of continuous saline bladder irrigation on preventing intravesical recurrence after undergoing radical nephroureterectomy for patients with upper tract urothelial carcinoma: a prospective, randomized controlled trial

Clinical efficacy of continuous saline bladder irrigation on preventing intravesical recurrence after undergoing radical nephroureterectomy for patients with upper tract urothelial carcinoma: a prospective, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016512
Enrollment
Unknown
Registered
2018-06-05
Start date
2018-07-01
Completion date
Unknown
Last updated
2018-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper Tract Urothelial Carcinoma

Interventions

1:continuous saline bladder irrigation
2:non-irrigation
3:continuous low dose of bladder instillation of mitomycin

Sponsors

Departmeng of Urology, Changhai Hospital Affiliated by the Second Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with UTUC (ureter pelvic or ureter); 2. Aged range from 18 to 75 years; 3. Assign informed consent.

Exclusion criteria

Exclusion criteria: 1. History of urothelial carcinoma; 2. With local lymph node invasion; 3. With distant metastasis; 4. With bladder cancer; 5. With other kinds of cancer; 6. Receiving neoadjuvant chemotherapy before operation; 7. Receiving systemic chemotherapy after operation; 8. Receiving radiotherapy after operation; 9. Loss to follow up; 10. Dysfunction of cardiac, liver, or renal.

Design outcomes

Primary

MeasureTime frame
intravesical recurrence;—

Countries

China

Contacts

Public ContactChuanliang Xu

Departmeng of Urology, Changhai Hospital Affiliated by the Second Military Medical University

13761178177@163.com+86 13761178177

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026