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Effect of pre- and peri-operative hypovolemia on postoperative outcomes in patients undergoing elective colorectal cancer surgery

Effect of pre- and peri-operative hypovolemia on postoperative outcomes in patients undergoing elective colorectal cancer surgery

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800016510
Enrollment
Unknown
Registered
2018-06-05
Start date
2018-06-05
Completion date
Unknown
Last updated
2018-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elective colorectal cancer surgery under general anesthesia

Interventions

Preoperation dehydration and postoperation dehydration group:Urine and blood before and after operation room are collected separately
Preoperation dehydration and postoperation normal group:Urine and blood before and after operation room are collected separately
Preoperation normal and postoperation dehydration group:Urine and blood before and after operation room are collected separately
Preoperation normal and postoperation normal group:Urine and blood before and after operation room are collected separately

Sponsors

Shaoxing People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients familiar with all the procedure and evaluation, agreed to participate in this experiment,and sign the informed consent; 2) ASA I-II scheduled under general anesthesia; 3) Body mass index (BMI) is between 18-25; 4) Patients aged all years of age, male or female.

Exclusion criteria

Exclusion criteria: 1) Patients with urinary system diseases before operation; 2) Patients with ASA class more than grade II, severe cardiac, lung, hepatic and renal diseases; 3) Preoperative cognitive dysfunction in patients; 4) The intraoperative blood loss is more than 200ml, shock or other rescue accidents.

Design outcomes

Primary

MeasureTime frame
Urine color;Urine specific gravity;Urine osmotic pressure;Urinary creatinine concentration;Postoperative complications and mortality;

Secondary

MeasureTime frame
Serum creatinine concentration;Blood osmotic pressure;Blood urea nitrogen;

Countries

China

Contacts

Public ContactLi Yuhong

Shaoxing People's Hospital

yuh_li@qq.com+86 13758147990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026