oral lichen planus
Conditions
Interventions
Group A:0.01% compound betamethasone mouth rinse
Group B:0.02% dexamethasone mouth rinse
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. OLP patients aged 18-60 years old; 2. Acute extensive or multi-focal erosion and the lesion size exceeding 1 square centimeter; 3. Disease-process exceeding 2 months; 4. Result of a physical examination is normal; 5. Negative reaction to pregnancy test in women; 6. Subject decided independently to participate in the study ,get rid of bad habits and follow the doctor's advice.
Exclusion criteria
Exclusion criteria: 1. Those with severe systemic diseases that can not control by medicine; 2. History of allergies to glucocorticoids; 3. Those taking immunotherapy during the previous 3 months; those having topical treatment of lichen planus within a week 4. Lichenoid disease induced by amalgam or other drugs; 5. Those with other severe mucous diseases; 6. Intention of pregnancy or lactation; 7. Using of contraceptives of steroid hormone recently; 8. Those with history of psychiatric disorders who can not to cooperate .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lesion size;pain level;plasma concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| healing rate;recurrence rate; | — |
Countries
China
Contacts
Public ContactHongmei Zhou
Outcome results
None listed