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Clinical study of ultrasound guided BTX-A in the treatment of salivation after stroke

Clinical study of ultrasound guided BTX-A in the treatment of salivation after stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016502
Enrollment
Unknown
Registered
2018-06-06
Start date
2018-09-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post stroke saliva

Interventions

Experimental group:Routine training + BTX-A injection

Sponsors

Affiliated rehabilitation hospital of Fujian University of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) the clinical, MRA and cervical vascular ultrasound or the head and neck CTA or total cerebral angiography DSA were all conformed to the diagnostic criteria of cerebrovascular disease diagnosed in the Fourth Academic Conference on cerebrovascular disease in 1995; (2) aged between 40-80 years old; (3) saliva with different degrees of dysphagia; (4) the patient is not in the acute stage, the vital signs are stable, the condition is stable, consciousness is sober, can cooperate with the treatment; (5) patients or family members participate voluntarily and sign informed consent.

Exclusion criteria

Exclusion criteria: (1) patients who do not conform to the criteria for inclusion; (2) patients with myasthenia gravis, multiple sclerosis, congenital ptosis and other neuromuscular disorders. (3) merger of heart, liver and kidney insufficiency, physical weakness, active pneumonia, blood disease, connective tissue disease, pregnancy and lactation; (4) in the recent 2 weeks, there will be drugs that interact with botulinum toxin; (5) patients who had botulinum toxin in the past three months; (6) allergic to any component of toxin products or allergic constitution; (7) Patients with mental illness.

Design outcomes

Primary

MeasureTime frame
Saliva frequency score;Parotid and submandibular gland size;

Countries

China

Contacts

Public ContactXue Xiehua

Affiliated Rehabilitation Hospital of Fujian University of traditional Chinese Medicine

465356738@qq.com+86 13067351145

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026