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Research on related factors of acute toxicities with rotational IMRT for head and neck cancer

Research on related factors of acute toxicities with rotational IMRT for head and neck cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016495
Enrollment
Unknown
Registered
2018-06-05
Start date
2016-01-01
Completion date
Unknown
Last updated
2018-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer

Interventions

1:Helical tomotherapy
2:RapidArc
3:SmartArc

Sponsors

Department of Radiation Oncology, Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 75 years; 2. The pathological diagnosis is squamous cell carcinoma; 3. Patients diagnosed cancer of the larynx,hypopharynx and oropharynx are staged retrospectively from III to IVA, in accordance with the American Joint Committee on Cancer 2010 criteria. Or refuse operation; 4. Normal blood picture and hepatorenal function; 5. No severe and /or uncontrolled medical conditions, including severe cardiovascular disease, uncontrolled diabetes and high blood pressure, active infection, liver and kidney disorders; 6. No second primary carcinoma; 7. Karnofsky scoring function from 80 to 100.

Exclusion criteria

Exclusion criteria: 1. Severe and /or uncontrolled medical conditions, including severe cardiovascular disease, uncontrolled diabetes and high blood pressure, active infection, liver and kidney disorders; 2. Patients in pregnant or nursing; 3. Received any surgical operation or radiotherapy; 4. Patient with uncontrollable mental disease and active infection; 5. Documented hypersensitivity reaction to paclitaxel or taxinol; 6. Patient with lower compliance; 7. Patient not fitted for this study determined by the principal investigator (PI).

Design outcomes

Primary

MeasureTime frame
acute toxicities;

Countries

China

Contacts

Public ContactBoning Cai

Chinese PLA General Hospital

cbn0922@163.com+86 13691346630

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026