Atrial Fibrillation
Conditions
Interventions
New Oral Anticoagulant Group 1:Randomly administered initial heparin doses of 110 U/kg
Warfarin group:100 U/kg initial heparin dose
New Oral Anticoagulant Group 2:120 U/kg initial heparin dose
New Oral Anticoagulant Group 3:130 U/kg initial heparin dose
Sponsors
First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years male and female; 2. First time radiofrequency ablation of atrial fibrillation; 3. Electrocardiogram, 24-hour dynamic electrocardiogram or ECG monitoring proved to be atrial fibrillation. 4. Patients receiving warfarin have INR between 2-3.
Exclusion criteria
Exclusion criteria: 1. Past cardiac surgery or intracardiac device implantation; 2. Left heart ejection fraction 55mm; 3. Moderate to severe valvular heart disease; 4. Reduced renal function (creatinine clearance 3); 5. Patients with acute coronary syndrome taking antiplatelet drugs; 6. Moderate to severe anemia (hemoglobin <90g/l); 7. Life expectancy less than 1 year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Activated Clotting Time (ACT); | — |
Countries
China
Contacts
Public ContactWang Na
Outcome results
None listed