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Effect of Preloading Alkalinized Lidocaine in Endotracheal Tube Cuffs on the Complications of Throat After Brief Surgery

Effect of Preloading Alkalinized Lidocaine in Endotracheal Tube Cuffs on the Complications of Throat After Brief Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800016482
Enrollment
Unknown
Registered
2018-06-04
Start date
2018-07-01
Completion date
Unknown
Last updated
2018-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endotracheal tube

Interventions

group A:Cuffs will be prefilled >90 minutes before intubation with 10 mL of air .Cuffs will be emptied immediately before intubation. After intubation,endotracheal tube cuffs will be injected into the
saline group (group B):Cuffs will be prefilled >90 minutes before intubation with 10 mL of saline .Cuffs wil be emptied immediately before intubation. After intubation,endotracheal tube cuffs will be
lidocaine group (group C):Cuffs will be prefilled >90 minutes before intubation with 4 mL of 2% lidocaine solution and 6 mL of 5% sodium bicarbonate solution .Cuffs will be emptied immediately before

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. ASA I ~ II; 2. Patients between the ages of 20 and 60 years; 3. patients who are scheduled for gynecology surgery requiring general anesthesia and endotracheal intubation from July 2018 to February 2019 at the Affiliated Hospital of Xuzhou Medical University; 4. no respiratory disease.

Exclusion criteria

Exclusion criteria: 1. Preoperative cough, hoarseness, sore throat, difficulties in tracheal intubation, history of mouth or pharynx surgery; 2. Wheezing or speech impairment; 3. Nasal feeding or indwelling stomach tube; 4. Steroid treatment is being used; 5. allergic to lidocaine.

Design outcomes

Primary

MeasureTime frame
cough;hoarseness;sore throat;

Secondary

MeasureTime frame
heart rate;blood pressure;

Countries

China

Contacts

Public ContactGongjian Liu

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University

liugongjian61@hotmail.com+86 13952203528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026