Malignant tumor of extrahepatic bile duct
Conditions
Interventions
Group ENBD:Endoscopic Nasobiliary Drainage
Group PTBD:Percutaneous Transhepatic Biliary Drainage
Group EBS:Endoscopic Biliary Stenting
Sponsors
General surgery department, Zhongshan hospital affiliated Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients who meet the following four criteria are included into the study: 1) Preoperative clinical diagnosis of hilar cholangiocarcinoma, distal bile duct cancer, periampullary cancer without distant metastasis or peripheral vascular invasion, and plann for radical surgery; 2) Serum total bilirubin greater than 51 umol/l; 3) Aged 18 to 80 years old; 4) Sign in informed consent to receive preoperative PTBD, ENBD, EBS or without PBD.
Exclusion criteria
Exclusion criteria: If any of the following items are combined, the subject cannot enter the study: 1) Incorporate severe mental illness, severe heart, lungs and kidneys disease, etc., and be unable to tolerate surgery; 2) Malignant obstructive jaundice caused by metastatic tumors; 3) Pregnancy or lactation women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complication rate of PBD;success rate of PBD;Perioperative complication rate;Liver function recovery efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation metastasis rate;operation time;Bleeding amount of surgery;edema of Hepatoduodenal ligament;mortality of perioperative period;postoperative hospital stay;Total hospitalization costs;Total length of stay in hospital; | — |
Countries
China
Contacts
Public ContactHoubao Liu
General surgery department, Zhongshan hospital affiliated Fudan University
Outcome results
None listed