Lung Cancer
Conditions
Interventions
low background dose group:oxycodone hydrochloride low background dose
conventional background dose group:oxycodone hydrochloride conventional background dose
Sponsors
Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Anesthesiology, Peking University Cancer Hospital & Institute, Beijing
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (1) >18 and <65 years; (2) Patients without history of drug abuse; (3) Lung operation for the first time; (4) No chemotherapy or radiotherapy before operation; (5) Has no disease in immunological system.
Exclusion criteria
Exclusion criteria: (1) Does not want to receive oxycodone for postoperative analgesia; (2) A patient who has participated in a clinical trial in recent four weeks; (3) A patient who cannot cooperate with completion of study plan, including a patient unable to understand and express analgesic scores or with language difficulty; (4) an infectious disease or a conscious disorder; (5) Has a serious liver, kidney, brain or lung disease before operation; (6) Body mass index > 30 kg/m2 or <18kg/m2; (7) Has a history of drug abuse.(8)Have a history of chronic pain;(9) pregnant woman
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS postoperative; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative total dose of analgesic pump at each time point postoperation;Postoperative titration oxycodone hydrochloride dose;Analgesic satisfaction score; | — |
Countries
China
Contacts
Public ContactJiheng Chen
Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Anesthesiology,Peking University Cancer Hospital & Institute, Beijing
Outcome results
None listed